Poison (Material)

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Poison is a dark purple liquid material that stains creatures with the Effect poisoned.png Poisoned effect, doing small amounts of damage over time. While the stain itself cannot kill you or other creatures under normal conditions, the material itself can do appreciable amounts of contact damage. It will quickly evaporate on its own, creating Poison Gas if burned.

It can be washed off with Water, just like Toxic Sludge.


Poison never appears naturally. It is only created by spells, enemies or alchemical reactions, most notably by Myrkkyhiisi in the Underground Jungle. Apart from the poisonous plant bulbs that can grow in the Underground Jungle, there are no barrels or other containers filled with poison and no vats or pools naturally occur, making this substance a fairly rare occurrence outside of player spells like Poison Arc or Poison Trail. It can also spawn as a result of Fungal Shift.


Poison damage from the Effect poisoned.png Poisoned effect deals damage of 2% of your HP per hit in NG. With each cycle of New Game + damage triples.

For example on NG+++ poison will deal 54% of HP damage per tick. By NG+4 this can instantly kill you.

You take material damage from being in contact with the liquid, dealing 0.025 damage per tick, for each pixel touching your hitbox. Fully submerging in it would deal 144 material damage per second. The amount of damage this deals to other creatures varies between different species. This contact damage is not poison, but material damage, meaning it isn't scaled by nightmare or new game plus.

Poison Gas

Poison Gas is a gaseous Material that emits from evaporating poison liquid. It's flammable, but contrary to the name not actually poisonous. It has a dark purple color, similar to the poison it emits from. Functionally, it is identical to Flammable Gas.


  • The Freeze Field perk can be use to neutralize liquid poison, as frozen poison does not inflict stains, and you do not take any material contact damage from it, unlike Toxic Ice or Frozen Acid.


Like most liquids, it can also be a component for the random Alchemy recipes.

Reaction Rate Reagents Products
90 [fire] + [meltable_to_poison] [fire] + Poison
70 [lava] + Poison Poisonous Rock + Poison Gas
80 [lava] + [meltable_to_poison] [lava] + Poison
10 Blood + Poison Slime + Smoke
10 Blood + Poison Gas Slime + Smoke
60 Glue + [fire] [fire] + Poison Gas
50 Honey + Diamond Ambrosia + Poison
50 Meat + Poison Rotten Meat + Poison
15 Poison + Air Poison Gas + Air
50 [acid] + Poison [acid] + Flammable Gas
80 Purifying Powder + Poison Purifying Powder + Water
40 [fire] + Poison Gas [fire] + Fire
80 [lava] + Poison Gas [lava] + Fire
100 Corrupted Rock + Frozen Poison Corrupted Rock + Corrupted Rock
100 Draught of Midas + Frozen Poison Draught of Midas + Gold
90 Gas of Midas + Frozen Poison Gold + Gold
50 [acid] + Frozen Poison [acid] + Flammable Gas
3 Steam + Frozen Poison Water + Frozen Poison
50 [molten_metal] + Frozen Poison Metal Dust + Frozen Poison
50 Molten Brass + Frozen Poison Brass + Frozen Poison
50 Molten Copper + Frozen Poison Copper + Frozen Poison
50 Molten Gold + Frozen Poison Gold + Frozen Poison
50 Molten Metal (Steel) + Frozen Poison Steel (Powder) + Frozen Poison
50 Molten Silver + Frozen Poison Silver + Frozen Poison
50 Molten Wax + Frozen Poison Wax + Frozen Poison


Poison Trail and Bubble Spark being used to generate large amounts of Poison.

See Also