Skeleton Boss
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This boss can be found in the Frozen Vault Orb Room. It is a pretty easy and harmless boss and shouldn't be too hard to kill.
It can throw a chain and an occasional toxic sludge orb.
Touch of spells can be used to easily kill this boss as it is not immune to their instant-kill effect, however, you may need piercing to read his center point due to the boss's size, additionally, aim for the head.